The 21 actors in the Sexy Issue of TV Guide Magazine are:
Patrick Dempsey Evangeline Lilly
Justin Chambers Eva Longoria
Shemar Moore Rebecca Romijn
Josh Holloway Sendhil Ramamurthy
Katherine Heigl Roselyn Sanchez
James Tupper Dave Annable
Rashida Jones Taylor Kitsch
Minka Kelly Marg Helenberger
Skeet Ulrich Jennifer Morrison
Eric Mabius Ali Larter
Nadine Velzaquez
Patrick Dempsey Evangeline Lilly
Justin Chambers Eva Longoria
Shemar Moore Rebecca Romijn
Josh Holloway Sendhil Ramamurthy
Katherine Heigl Roselyn Sanchez
James Tupper Dave Annable
Rashida Jones Taylor Kitsch
Minka Kelly Marg Helenberger
Skeet Ulrich Jennifer Morrison
Eric Mabius Ali Larter
Nadine Velzaquez