Mayim Bialik, best known as "Blossom," which ran on NBC on Monday nights in the 90's, will guest-star as a potential love interest for Jim Parsons' character Sheldon on "The Big Bang Theory," which also airs on Monday nights, but on CBS. Bialik is a real-life Ph.D in neuroscience. She is described as the female version of Sheldon. Executive Producer Bill Prady says, "The way he deals with her will be consistent with the way he deals with the world up until now, He won't not be Sheldon. She'll be someone he certainly appreciates."